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Sources: Pickart & Margolina, Int J Mol Sci 2018 (PMID: 29986520) | Pickart et al., BioMed Res Int 2015 (PMID: 26236449) Security Profile & Chemical Identity Molecular specifications and documented tolerance in clinical studies GHK-Cu Chemical Identity Natural copper complex of the tripeptide glycyl-L-histidyl-L-lysine GHK-Cu Tolerance & Status Safety data from clinical and cosmetic studies Published Clinical & Preclinical Data Key studies published in Int J Mol Sci, BioMed Res Int and dermatological journals -55.8% Reduction in wrinkle volume after 12 weeks of topical application of GHK-Cu cream Anti-Aging Results (12 weeks) 4 000+ Human genes modulated by GHK-Cu (31.2% of the genome) Genomic Impact + 70 % Increased collagen synthesis in human skin fibroblasts Collagen Stimulation Comparison Published Clinical & Preclinical Data Key studies published in Int J Mol Sci, BioMed Res Int and dermatological journals -55.8% Reduction in wrinkle volume after 12 weeks of topical application of GHK-Cu cream Anti-Aging Results (12 weeks) 4 000+ Human genes modulated by GHK-Cu (31.2% of the genome) Genomic Impact + 70 % Increased collagen synthesis in human skin fibroblasts Collagen Stimulation Comparison Important Notice Search Only Not intended for human consumption

for the parallel TB-500 review, see TB-500 cellular migration and tissue repair

2001 Sep;131(9 Suppl):2515S-22S

Cell 83 , 31553170.e3158 (2023)

In this 160th episode, I riff a bit on a book my former Ju-Jitsu Sensei wrote and gifted to me many years back